Molecular and ionic mimicry and the transport of toxic metals
نویسندگان
چکیده
منابع مشابه
Molecular and ionic mimicry and the transport of toxic metals.
Despite many scientific advances, human exposure to, and intoxication by, toxic metal species continues to occur. Surprisingly, little is understood about the mechanisms by which certain metals and metal-containing species gain entry into target cells. Since there do not appear to be transporters designed specifically for the entry of most toxic metal species into mammalian cells, it has been p...
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Intracellular concentrations of essential metals are normally maintained within a narrow range, whereas the nonessential metals generally lack homeostatic controls. Some of the factors that contribute to metal homeostasis have recently been identified at the molecular level and include proteins that mediate import of essential metals from the extracellular environment, those that regulate deliv...
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Cadmium is a toxic heavy metal which can cause numerous alterations in cell functioning. Exposure to cadmium leads to generation of reactive oxygen species, disorders in membrane structure and functioning, inhibition of respiration, disturbances in ion homeostasis, perturbations in cell division, and initiation of apoptosis and necrosis. This heavy metal is considered a carcinogen by the Agency...
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the survey of the virtual higher education in iran and the ways of its development and improvement
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2005
ISSN: 0041-008X
DOI: 10.1016/j.taap.2004.09.007